ASM 2019

Invited Talk (I16)

8/3/2019, 3:15 pm - 3:45 pm in LH 310


Arnab Mukherjee

Associate Professor, IISER Pune

E-mail: arnab.mukherjee[at]iiserpune.ac.in

 

Brief Bio-sketch:

Received Ph.D. in theoretical chemistry from IISc Bangalore on 2005. Then I went for postdoctoral research in ENS, Paris and University of Colorado, Boulder with J. T. Hynes. I joined IISER Pune as assistant professor on 2009.

DNA STRUCTURE FROM ITS SEQUENCE USING BASE-STEP FREE ENERGY AND MACHINE LEARNING

In this talk, I will discuss about the prediction of DNA structures from its sequence using two different approaches: a statistical mechanical approach and a machine learning approach. While the free energy cost of BA DNA transition at the dinucleotide level was used to predict the 'B' or 'A' DNA in the statistical mechanical model, a machine learning approach based on classification algorithm was used to predict the structure from the sequence. Finally, we will show a correspondence between both the approaches.

 

Invited Speakers Program